• Vaccine Price Reduction Announcement
• Bharat Biotech International Ltd. (BBIL) and GSK pledged to reduce the price of the RTS,S malaria vaccine to below USD 5 by 2028.
Enabled through:
• Higher production capacity
• Cost-effective manufacturing
• Low-margin pricing strategy
• Linked to the Gavi 6.0 replenishment period (2026–2030).
Manufacturing & Technology Transfer
• RTS,S is the first malaria vaccine recommended by the WHO (in 2021).
• GSK developed the vaccine in partnership with PATH and others.
• GSK began technology transfer to Bharat Biotech in 2021.
• Full transition of manufacturing to BBIL expected by 2028.
• Bharat Biotech has invested over USD 200 million in vaccine production infrastructure.
Global Rollout and Impact
• With Gavi’s support, 12 African countries are set to integrate RTS, S into routine immunisation by end of 2025.
WHO’s Malaria Vaccine Implementation Programme (MVIP) data (2019–2023) showed:
• 13% reduction in all-cause mortality
• 22% reduction in severe malaria hospitalisations among vaccinated children
• 75% prevention of malaria episodes when combined with seasonal chemoprevention
Broader Strategy for Malaria Control
• RTS, S is used alongside WHO-recommended tools: chemoprevention, treatments, indoor spraying (IRS), and bed nets.
• GSK is also developing a second-generation malaria vaccine, targeting a different parasite stage.
Collaborative Effort
• Stakeholders involved: GSK, Bharat Biotech, Gavi, WHO, PATH, MedAccess, and African implementing countries.
• Aimed at sustained affordability, access, and equity in vaccine delivery.